Neutrophil to lymphocyte ratio (NLR) in COVID-19 patients

Document Type : Original Article

Authors

1 National Cancer Research Center, University of Baghdad, Iraq

2 Department of Microbiology, College of Medicine, University of Diyala, Iraq

3 Microbiology Department, College of Medicine. University of Wasit, Iraq

4 Dentistry college, Al-Mustaqbal University, Iraq

Abstract

Background: Inflammation assumes a significant part in the spread of Coronavirus. Individuals tainted with Coronavirus are known to have a resistant framework that is dysregulated and can cause strange in blood cells count and platelets consider an indication of irritation. This study explores associations between COVID-19 severity, C-reactive protein concentration levels and neutrophil to lymphocyte ratio. Methods: Cross-sectional study included 68 cases with COVID-19 (36 males and 32 females; their age ranged between 20-70 years old), who were admitted to Al-Zahra Teaching Hospital in Al-Kut city - Iraq, from March 2020 until December 2020. Nasopharyngeal swabs were collected from all patients for RNA extraction and real time polymerase chain reaction processing as well as blood samples were collected in white blood cells count and C-reactive protein. Results: Most patients with COVID-19 were noticed among males 36 (52.95%) than females 32 (47.05%), and among age group 51-60 years old was 21(30.88%). There is a significant difference in level of C- reactive protein and neutrophil to lymphocyte ratio in the binging of the infection and after 14 days of infection. Conclusion: The number of lymphocytes and neutrophil very in patients with COVID-19 and can use it as interpreters the severity of infection. T test and p value at significance level 0.05 used to test the correlation.

Keywords