Langya virus - Recent insights into emerging Henipavirus

Document Type : Review Article

Author

1 Department of Biotechnology, Karpagam Academy of Higher Education, Coimbatore, 641021, Tamil Nadu, India

2 Centre for Natural Products and Functional Foods, Karpagam Academy of Higher Education, Coimbatore, 641021, Tamil Nadu, India

Abstract

Background: Zoonotic diseases and emerging infectious diseases pose a major global health burden and cause huge challenge to both human and animal health. The recent identification of Langya virus, a novel zoonotic pathogen originating from the Langya region of China raises concerns about emerging zoonotic diseases. This virus has been identified in febrile patients in eastern China, where shrews are suspected as the natural reservoir. The virus belongs to the Paramyxoviridae family. Langya virus has attracted significant attention, as it shares similarities with other henipaviruses such as Nipah and Hendra viruses, which are recognized for their high pathogenicity in animals and humans. Although it shares similarities with previously identified henipaviruses, the Langya virus remains poorly understood. The initial findings indicated that there is no human-to-human transmission. However, comprehensive research is essential to elucidate its clinical progression, transmission dynamics, and broader implications for public health. This identification of new virus underscores the importance of continued active surveillance among both human and animal population and preparedness to effectively manage emerging pathogens like Langya virus.

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