Estimation of biofilm forming and antibiotic resistance of clinical Stenotrophomonas maltophilia in Ninawa hospitals, Iraq

Document Type : Original Article

Authors

1 Department of Anesthesia Techniques, Mosul Medical Technical Institute, Northern Technical University, Iraq

2 Department of Medical Laboratory Technologies, Mosul Medical Technical Institute, Northern Technical University, Iraq

3 Department of Pharmacy Technologies, Mosul Medical Technical Institute, Northern Technical University, Iraq

Abstract

Stenotrophomonas maltophilia is an emerging multiresistant nosocomial pathogen. This study aimed to isolate S. maltophilia and estimate the frequency of biofilm forming as a virulence factor contributing with resistance to some antibiotics. A total of 350 samples were collected from (100) patients in different hospitals of Mosul city during the period from April 2022 to June 2023. Using conventional methods and Vitek 2 automated System, the highest isolation rate of S.maltophilia was from blood samples as a 15%, urine and wound 28%, 20% respectively while there was no isolation from pharynx samples, the discs diffusion method used to confirm the resistant of bacterial strains against 10 antimicrobial agents, most of the stains were resistant to Ciprofloxacin (85.7%), Cefepime (71.4) and Ceftazidine (62.8), resistance level were > 60 % for all tested antimicrobial agents and were sensitive to Imipenem (42.8). The biofilm formation was implemented using microtiter plate method, almost (31.43%) were resistance to ciprofloxacin, fluroquinolon gentamicin and pipracillin and (42.85%) of S.maltophilia induced strong and moderate level biofilm which referring to the Intensity of virulence of this bacteria relating with serious nosocomial infections.

Keywords

Main Subjects

Microbes and Infectious Diseases

Articles in Press, Accepted Manuscript
Available Online from 10 June 2024

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