Bacteria biofilms: Navigating the way forward

Document Type : Letter to the Editor


1 Department of Chemical Pathology, School of Medical Laboratory Science, Usmanu Danfodiyo University Sokoto, Nigeria

2 Department of Immunology, School of Medical Laboratory Science, Usmanu Danfodiyo University Sokoto, Nigeria

3 Department of Medical Microbiology, School of Medical Laboratory Science, Achievers University Owo, Ondo State, Nigeria


For years now, microbial communities caused by biofilms have impacted antimicrobial efficacy and efficiency, with a concomitant increase in morbidity and mortality rates. This letter addresses the scientific aspect of how bacteria have evolved to promote their growth and survival against antimicrobial agents’ action. Key challenges that have led to serious problems in healthcare service delivery, particularly in developing countries, are the inability to culture biofilms in the laboratory, their complexity, high tolerance, and the presence of biofilm structures on both biotic and abiotic surfaces. In addition, infectious disease persistence in humans and animals highlights the need for a more effective approach towards curbing antimicrobial resistance and achieving One Health. Understanding the role of biofilm in microbial infections and the inherent tolerance and resistance to antimicrobial treatment are particular to public health and informed clinical decision-making. This letter emphasizes the urgent need to adopt a scientific approach to address the challenges posed by biofilms through the implementation of preventive measures and a better understanding of their comparative structure. With this, we can reduce its potential impact on global health and effectively manage this emerging threat.


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