• Home
  • Browse
    • Current Issue
    • By Issue
    • By Author
    • By Subject
    • Author Index
    • Keyword Index
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Peer Review Process
  • Guide for Authors
  • Submit Manuscript
  • Reviewers
  • Contact Us
 
  • Login
  • Register
Home Articles List Article Information
  • Save Records
  • |
  • Printable Version
  • |
  • Recommend
  • |
  • How to cite Export to
    RIS EndNote BibTeX APA MLA Harvard Vancouver
  • |
  • Share Share
    CiteULike Mendeley Facebook Google LinkedIn Twitter
Microbes and Infectious Diseases
arrow Articles in Press
arrow Current Issue
Journal Archive
Volume Volume 3 (2022)
Issue Issue 3
Issue Issue 2
Issue Issue 1
Volume Volume 2 (2021)
Volume Volume 1 (2020)
Mohamed, E., Ebeid, K., Mohamed, D., ELsaka, A., Samy, S. (2022). Microbiological assessment of COVID-19 associated acute invasive fungal rhinosinusitis: A tertiary hospital based study. Microbes and Infectious Diseases, 3(3), 522-533. doi: 10.21608/mid.2022.130002.1268
Esraa A Mohamed; Kamal Ebeid; Dareen Mohamed; Ayman ELsaka; Sara Samy. "Microbiological assessment of COVID-19 associated acute invasive fungal rhinosinusitis: A tertiary hospital based study". Microbes and Infectious Diseases, 3, 3, 2022, 522-533. doi: 10.21608/mid.2022.130002.1268
Mohamed, E., Ebeid, K., Mohamed, D., ELsaka, A., Samy, S. (2022). 'Microbiological assessment of COVID-19 associated acute invasive fungal rhinosinusitis: A tertiary hospital based study', Microbes and Infectious Diseases, 3(3), pp. 522-533. doi: 10.21608/mid.2022.130002.1268
Mohamed, E., Ebeid, K., Mohamed, D., ELsaka, A., Samy, S. Microbiological assessment of COVID-19 associated acute invasive fungal rhinosinusitis: A tertiary hospital based study. Microbes and Infectious Diseases, 2022; 3(3): 522-533. doi: 10.21608/mid.2022.130002.1268

Microbiological assessment of COVID-19 associated acute invasive fungal rhinosinusitis: A tertiary hospital based study

Article 4, Volume 3, Issue 3, August 2022, Page 522-533  XML PDF (630.21 K)
Document Type: Original Article
DOI: 10.21608/mid.2022.130002.1268
Authors
Esraa A Mohamed email 1; Kamal Ebeid2; Dareen Mohamed3; Ayman ELsaka3; Sara Samy4
1Department of medical microbiology and immunology, Faculty of Medicine, Tanta University, Egypt
2Department of Otorhinolaryngology, Faculty of Medicine, Tanta University, Egypt
3Department of Pathology, Faculty of Medicine, Tanta University, Egypt
4Department of Medical Microbiology and Immunology, Faculty of Medicine, Tanta University, Egypt
Abstract
Background:  Acute invasive fungal rhinosinusitis (AIFRS) is an emerging disease on top of SARS CoV-2 virus infection and associated with severe and fatal prognosis especially in the presence of other immunosuppressive conditions. Aim of study: Identification of the causative agents of AIFRS in COVID-19 patients and its impact on the survival outcome. Methods: This retrospective study was carried out on 70 clinically and radiologically diagnosed AIFRS patients either in concomitant with COVID-19 infection or following recovery. Exudates from the lesions were collected during surgical debridement. Both microbiological and pathological examinations were done to identify the type of the causative fungi followed by assessment of the relation between different type of fungi and the outcome in the affected patients. Results: Positive fungal cultures were detected in 54 cases out of 70 where Mucor species were the most common isolates (42 patients) and only 12 cases were proven to be Aspergillus species. All patients were diabetic and under steroid therapy. Mortality rate was 42.9% and 25% in mucormycosis and aspergillosis respectively. High dose of steroid together with Mucor species infection were the most important risk factors in determining the prognosis and the outcome of the infection. Conclusion: Microbiological diagnosis together with other methods plays an important role in accurate and rapid diagnosis of AIFRS in association with COVID-19 for proper management and improving the outcome.
Keywords
AIFRS; COVID-19; Mucormycosis; Aspergillosis
Main Subjects
Medical mycology; Medical virology
Statistics
Article View: 103
PDF Download: 67
Home | Glossary | News | Aims and Scope | Sitemap
Top Top

Journal Management System. Designed by NotionWave.