Prevalence and antimicrobial resistance pattern of Acinetobacter baumannii isolates from intensive care units in Zagazig University Hospitals

Salama, Safia; Hadhoud, Alaa; Lotfy, Wael E; Anis, Reham Hassan

doi:10.21608/mid.2021.57273.1110

Prevalence and antimicrobial resistance pattern of Acinetobacter baumannii isolates from intensive care units in Zagazig University Hospitals

Document Type : Original Article

Authors

¹ Department of Medical Microbiology and Immunology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

² General Surgery Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

10.21608/mid.2021.57273.1110

Abstract

Background:Multidrug resistant (MDR) Acinetobacter baumannii (A. baumannii) has been recognized as a serious causative agent of health care associated infections (HAIs) in different countries of the world with increasing morbidity and mortality, therefore continuous monitoring and evaluation in health care settings are mandatory.We aimed to assess A. baumannii as a cause of HAIs in intensive care units (ICUs) of Zagazig University Hospitals and to demonstrate its antimicrobial resistance pattern. Methods: Different bacteriological specimens were collected from 71 patients with HAIs for isolation of A. baumannii, followed by invitro antibiotic susceptibility test. Results: Ten A. baumannii isolates were recovered (13.5%), of which eight isolates showed multidrug resistance pattern (80%). Prior use of antibiotics was a significant risk factor of development of multidrug resistance (P< 0.05). Conclusion: Predominance of MDR A. baumannii as an important agent of HAIs in ICUs of Zagazig University Hospitals. Inappropriate administration of antimicrobial agents appears to be the most important risk factor.

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