• Home
  • Browse
    • Current Issue
    • By Issue
    • By Author
    • By Subject
    • Author Index
    • Keyword Index
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Peer Review Process
  • Guide for Authors
  • Submit Manuscript
  • Reviewers
  • Contact Us
 
  • Login
  • Register
Home Articles List Article Information
  • Save Records
  • |
  • Printable Version
  • |
  • Recommend
  • |
  • How to cite Export to
    RIS EndNote BibTeX APA MLA Harvard Vancouver
  • |
  • Share Share
    CiteULike Mendeley Facebook Google LinkedIn Twitter
Microbes and Infectious Diseases
arrow Articles in Press
arrow Current Issue
Journal Archive
Volume Volume 2 (2021)
Issue Issue 1
Volume Volume 1 (2020)
Arogbodo, J., Fabowale, P., Osho, I. (2021). Evaluation of the antibacterial potential of ethyl alcohol leaf extract of Chrysophyllum albidum (G. Don) against five bacterial isolates. Microbes and Infectious Diseases, 2(1), 171-176. doi: 10.21608/mid.2020.44203.1065
Joseph Olowo Arogbodo; Paul Oluwatobi Fabowale; Innocent Bamidele Osho. "Evaluation of the antibacterial potential of ethyl alcohol leaf extract of Chrysophyllum albidum (G. Don) against five bacterial isolates". Microbes and Infectious Diseases, 2, 1, 2021, 171-176. doi: 10.21608/mid.2020.44203.1065
Arogbodo, J., Fabowale, P., Osho, I. (2021). 'Evaluation of the antibacterial potential of ethyl alcohol leaf extract of Chrysophyllum albidum (G. Don) against five bacterial isolates', Microbes and Infectious Diseases, 2(1), pp. 171-176. doi: 10.21608/mid.2020.44203.1065
Arogbodo, J., Fabowale, P., Osho, I. Evaluation of the antibacterial potential of ethyl alcohol leaf extract of Chrysophyllum albidum (G. Don) against five bacterial isolates. Microbes and Infectious Diseases, 2021; 2(1): 171-176. doi: 10.21608/mid.2020.44203.1065

Evaluation of the antibacterial potential of ethyl alcohol leaf extract of Chrysophyllum albidum (G. Don) against five bacterial isolates

Article 23, Volume 2, Issue 1, Winter 2021, Page 171-176  XML PDF (271.37 K)
Document Type: Original Article
DOI: 10.21608/mid.2020.44203.1065
Authors
Joseph Olowo Arogbodo email 1; Paul Oluwatobi Fabowale2; Innocent Bamidele Osho3
1Federal University of Technology Akure, Ondo State Nigeria. Department of Animal Production and Health
2Department of Microbiology, School of Sciences, Federal University of Technology, Akure
3Federal University of Technology Akure, Ondo State Nigeria. Department of Animal Production and Health
Abstract
Background: In contributing to solving the global challenge of antimicrobial resistance, an in- vitro experiment was conducted to evaluate the antibacterial potential of ethyl alcohol leaf extract of Chrysophyllum albidum (G. Don)against five clinical pathogenic microorganisms namely: Escherichia coli (EC), Proteus mirabilis (PM), Pseudomonas aeruginosa (PA), Staphylococcus aureus (SA), and Salmonella typhimurium (ST).Methods: Agar well diffusion method was adopted and the exhibited zones of inhibition by the isolates were measured, and taken as the antimicrobial potential of the extract. Phytochemical screening of the leaf extract revealed the presence of tannins, saponins, terpenoids, steroids, flavonoids and cardiac glycosides. Sixteen different concentrations (0.003 – 100 mg/mL) of the extract were prepared to establish the minimum inhibitory concentrations (MICs). Results: The MICs ranged between 0.006 - 0.195 mg/mL. SA with MIC of0.006 mg/mL was the most sensitive isolate to the extract while E. coli was actively resistant. PA was resistant to all the tested (control) commercial antibiotics but highly sensitive to the extractwith MIC of 0.195mg/mL. Conclusion: It was concluded that C. albidum is a medicinal plant possessing a broad spectrum antimicrobial activities and hence could be explored for the production of antibiotic by phyto-pharmaceutical establishments.
Keywords
Pathogenic bacteria; C. albidum; inhibition zone; antibiotic resistance
Statistics
Article View: 63
PDF Download: 38
Home | Glossary | News | Aims and Scope | Sitemap
Top Top

Journal Management System. Designed by NotionWave.